Hierarchical levels of the Evidence

What is “good for health”?
In case of Magnesium
Merit of knowledge
Credit

What is “good for health”?

Since the human body(and human social groups) is a complex system made of various components with in-between interactions, it is difficult for us to understand what is “good for health” or not. As usual when it comes to the complex problem, “divide and rule” is a good rule of thumb here. I divide it into four hierarchical layers, “Population“, “indivisuals“, “organs“, and “cells“.

Fig. 1 Understanding “good for your health” items by 4 levels of the spacial order of magnitude.

In case of Magnesium

Magnesium is a very well-known element known for over two centuries. However, the biological role in human body is still not fully understood and the investigation is under the way. Table 1. is my literature-organization(on the way) following the policy above.

Table 1. In case of Magnesium. * Historical anecdote, **contravertial, ***have apparent flaw.
Micro (cell)		Macro (Individual or small group of people, annecdotal)		Population (Cohort)
Muscle cells	Nerve cells	Muscle	Nerve	Muscle	Nerve(epilepsy)
TRPM6 shows 50% sequence homology with TRPM7 (also known as TRP-PLIK), which forms a Ca2+ and Mg2+-permeable cation channel.	***Ivannikov2011	*Dr. von Bärz’s rikshaw			Tymoor2019
	Kandel2014	*Hikyaku runners			Guo2023
	TRPM6 shows 50% sequence homology with TRPM7 (also known as TRP-PLIK), which forms a Ca2+ and Mg2+-permeable cation channel.	*Sakata female labourers			**UHiroshima2023

Merit of knowledge

Fig 2. shows why is it good for us to know.

Fig 2. Overview of the behavior selection: it is able to be typically applied to e.g. the financial investment or your daily meals.

Credit

Figures in Fig 1. (“The main elements constituting the human body” and the cell”) are generated with Google Gemini.